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Baycrest Impact Winter 2019

Baycrest Health Sciences & Baycrest Foundation Publications

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At Baycrest, she intends to focus on the link between depression and changes in the hippocampus, which is central to the process of remembering and imaging. "With repeated episodes of depression, the hippocampus actually starts to atrophy," she says. She plans to look at memory and imagination in older adults to discover what part of the imagination process is breaking down in depression and aging. "To be a Canada 150 Research Chair, you have to be among the best in the world," says Allison Sekuler, Baycrest's Vice-President of Research and Managing Director of the RRI. "Having Dr. Addis here opens up new avenues of exploration for us and strengthens our work in the area of mental health and aging. Depression is a risk factor for dementia, so Dr. Addis's research is a natural fit for our efforts to prevent dementia and help people live long and live well." Working collaboratively with neuroscientists and clinical researchers at Baycrest, Dr. Addis will look at what kinds of interventions or activities, or even brain stimulation, could allow people to imagine in a way that helps them in depression, and particularly, in aging. "I would like to investigate the potential for targeting brain networks that support memory and imagination to help people feel better about their future and increase their sense of well-being," she explains. "There are so many great initiatives going on at Baycrest - like the new Kimel Family Centre for Brain Health and Wellness and the Clinical Trials Unit - that are making it possible to take basic brain research into different directions. This is the place to be for memory research and the only place I would move halfway around the world to work." Visit baycrest.org to learn more about this program. 7

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