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BrainMatters-Fall/Winter_2020

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DEMENTIA RISK In addition to the impacts on mental health, we can't ignore the effects of the pandemic on other aspects of brain health, such as changes in memory. Baycrest researchers are looking at the possible effects of the COVID-19 pandemic on the trajectory to dementia in older adults. "The pandemic may increase the risk of developing dementia in two ways. First, through the virus' hallmark respiratory symptoms, there may be a decrease in oxygen going to the brain, which could have negative consequences and cause damage," says Dr. Jennifer Ryan, senior scientist at the RRI. "Emerging research from around the world is showing that being hospitalized and on a respirator has a negative impact on the brain." Adds Dr. Ryan, "Second, the infection prevention measure of physical distancing may result in social isolation for some individuals. This could lead to a depressive episode, and we know that depression increases the risk for mild cognitive impairment (MCI) and dementia later on." In this study, the researchers are making bi-weekly phone calls to healthy older adults living in the community and asking them about their mental health, their exercise and socialization levels, and their exposure to COVID-19. They are also testing these older adults' cognitive functions, like memory. The study is part of a larger research project looking at the factors that may predict which older adults ultimately develop MCI or dementia. "This study will increase our understanding of the risks posed to older adults' brain health during the pandemic," says Dr. Rosanna Olsen, scientist at the RRI. "The results should also help identify ways in which this group can be supported during these unprecedented times, for instance, through virtual social interactions, exercise programs or other COVID-safe activities." To support research at Baycrest, visit baycrest.org/donate Dr. Rosanna Olsen Dr. Jennifer Ryan Dr. Linda Mah BrainMatters FALL|WINTER 2020 15

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