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19 BAYCREST | 2024 PARTNERSHIPS FOR BRAIN HEALTH The Kimel Centre is the flagship dementia prevention location of the Canadian Consortium on Neurodegeneration in Aging (CCNA), a research initiative comprising more than 300 researchers across Canada. Together, we're working on a Brain Health PRO online education project to support people in improving their diet, exercise, and other strategies for preventing dementia. Initially, the project followed 350 people across Canada who were enrolled in a 12-month program. In the next phase of testing, Kimel Centre members will receive in- person programs and also use Brain Health PRO. Their progress will be compared to that of another 600 people across Canada who will only receive Brain Health PRO. By tracking activities, fitness regimes, and sleep patterns, our scientists will learn if this online program is an option that individuals can stick to, and whether they can alter their behaviours for the better. Researchers and scientists from across the country will also have access to the Kimel Centre, opening the potential for exciting and promising new research and treatments. HEATHY GUT, HEALTHY BRAIN Gum and mouth, gut, and brain health are related because abnormal bacteria in the mouth and gut can produce inflammation that affects the brain. A new study is analyzing the microbiome (DNA from the bacteria) of the mouth and gums in individuals with Alzheimer's disease and early forms of memory loss. The study hopes to demonstrate that a distinguishable subgroup of people with Alzheimer's disease show evidence of inflammation of the gums, and that this might require distinct therapies to delay progression of brain disease. Our researchers want to identify how a healthy gut, exercise and nutrition are connected to brain health, and, hopefully, motivate people to lead healthier lifestyles.

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